My research areas in the Switch lab encompass a series of topics.
My main topic is the prediction of molecular chaperone binding sites to understand the precise function of chaperones and the properties of its substrate proteins. We use an integrated method of experimental data and homology protein modeling to unravel the substrate-binding residue preferences of molecular chaperones.
Further, I recently developed a graphical interface for the FoldX forcefield as a YASARA plugin. This finally allows scientists to do free energy predictions entirely interactive in a 3D graphical environment without having to use the command line anymore.
Lastly, I am also involved in multiple molecular modeling projects with collaborating groups.